TEACHING EXPERIENCE :

Total teaching experience of more than three decades in various capacities in Department of Chemistry, University of Pune and as a full Professor for twelve years.

POST DOCTORAL FELLOWSHIP AND VISITS ABROAD :

Postdoctoral fellow (June 1979 to May, 1980) with Professor Dr. D. Seebach at Swiss Federal Institute of Technology (ETH), Zurich (Switzerland). Also visited several places in Germany, Italy and Switzerland.

ADMINISTRATIVE EXPERIENCE :

More than 15 years of administrative experience in various capacities in the department and university.

HONOURS :

Invited by various reputed institutes and universities for delivering series of lectures.

i) Academic Guest :

1. Swiss Federal Institute of Technology (ETH), Zurich,Switzerland, June to August, 1980.

2. Vikram Sarabhai Space Research Centre, Tiruvantpuram, December, 1984.
   

ii) UGC Visiting Fellow:

1. Shivaji University, Kolhapur, Jan 1993.

2. Sardar Patel University, Vallabhvidyanagar, Jan., 1994.

FELLOW AND MEMBERSHIP :

• Fellow of Maharashtra Academy of Sciences (FMASC).

• Member of Royal Society of Chemistry, London (MRSC).

• Life Member, Maharashtra Association for the Cultivation of Sciences, Pune.

AWARDS :

• Best Teacher Award, Pune Municipal Corporation, September, 1996.

• Prin. V. K. Joag Award for outstanding contribution in teaching and research, Pune University, February, 1997.

RESEARCH PUBLICATIONS :

Nearly 100 Papers including two reviews in international journals.

NUMBER OF STUDENTS GUIDED FOR RESEARCH DEGREES:

M.Phil. & Ph.D. : 31 (Out of which 9 students have been awarded Post-doctoral fellowships in foreign countries)

MEMBER OF ACADEMIC BODIES OF VARIOUS UNIVERSITIES :

Worked on various academic bodies of Pune University and other Universities. Some of these are indicated below :

• Management Council, University of Pune, Pune (1995-2000).

• Senate, University of Pune, Pune (1995-2000).

• Acting Dean Faculty of Science, University of Pune, Pune (2000-2001)

• Board of Studies in Chemistry, Devi Ahilya University, Indore (1994-97)

• Board of Studies in Chemistry, University of Pune, Pune (1995-2000)

• Board of Studies in Chemistry, North Maharashtra University, Jalgaon (1995-2000)

• Board of Studies in Chemistry, Shivaji University, Kolhapur (2000-2001)

• Board of Studies in Polymer Science, University of Pune, Pune (1995-1999).

• Board of Studies in Chemical Sciences, North Maharashtra University, Jalgaon (2001 --)

• Ph.D. Committee, University of Pune, Pune (1996-1998, 1999-2001)

• Ph.D. Committee, Bharati Vidyapeeth, Pune (1997-2001)

• Ph.D. Committee, Vikaram University, Ujjain (2000-2002)

• Research and Recognition Committee, North Maharashtra University, Jalgaon (2001)

• Faculty of Science, University of Pune, Pune (1995-1999).

• Board of Sports, University of Pune, Pune (1996-1999)

• Fee Revision Committee, University of Pune, Pune (1998-1999)

• Member and Chairman of Various Local Inquiry Committees to inspect the facilities available in the Colleges to consider their affiliation to University (since 1990).

• Member of a Committee to recommend teachers for State Awards (1996-2000)

• Post-graduate centralized admission Committee (1996 to 2000), Chairman (2001).

• Chairman - Centralized BCS Admission Committee (1999).

• Chairman - Local Inquiry Committee to check the facilities available in homeopathy colleges affiliated to the University of Pune.

• Worked as Vice-Chancellor's nominee on several selection and assessment committees appointed to select teachers and principals.

MEMBER OF VARIOUS COMMITTEES OF THE PUNE UNIVERSITY :

• Member, Grievance Committee, 1996-2000.

• Chairman, Grievance Committee, May, 1998, October, 2000.

• Budget Advisory Committee, 1998-1999, 1999-2000, 2000-2001.

• Member, Development Grants Committee, 1998, 1999.

• Chairman, Accommodation and Campus Development Committee, 1997-2000.

• Chairman, Canteen Committee, 1997-2000.

• Chairman, Refectory Advisory Committee, 1990-1994.

• Member, Lapses Committee, 2000-2001

• Chairman, Unfair Means Committee, 1999-2001

• Member, Purchase Committee, 1995-2000.

• Member, Board of Examination, 2000-2001

• Chairman, Furniture Committee (2001)

PRESIDENT, PUNE UNIVERSITY TEACHERS' FORUM ( 1988-1990) :

During this period Prof. Mali had close interaction with the teachers and has taken keen interest in solving their problems and motivating them for organizing workshops, symposia and seminars.

CO-ORDINATOR, U.G.C., NET (PUNE UNIT)

CSIR and U.G.C. jointly conduct the National Eligibility Test (NET) for post-graduate students. The assessment of answer books and preparation of result of Science faculty students is done by CSIR at New Delhi and for all students of arts, humanities and social sciences at Pune by U.G.C., NET Unit. More than 70,000 students appear for the U.G.C.-NET examinations. Prof. Mali was Co-ordinator of this unit(2000-2001). This is assigned to a person equivalent to Deputy Secretary of UGC on an honorary basis. The appointment was made by U.G.C. on recommendation of Honorable Vice-Chancellor of University of Pune.

CHIEF CO-ORDINATOR, PUNE UNIVERSITY GOLDEN JUBILEE COMMITTEE
(1998-1999):

During the period of Golden Jubilee year several activities were organized. Each of the following activity organized for students, teachers and nonteaching staff of colleges, university and for society was initiated and planned mainly by Prof.Mali as Chief Co-ordinator. The implementation was through other committees.

• 'SUSANWAD' Research Students' Seminar : In this seminar, more than 500 students from all subjects presented their work in presence of teachers and scientists in December, 1998.

• 'SUDARSHAN' Science Exhibition : Organized in January, 1999, received profound response from society, teachers and students. More than 2 lakh people visited the exhibition and appreciated it.

• Blood Donation Camp : It was inaugurated by Honourable Governor of Maharashtra Dr.P.C.Alexander. About 1000 students, teachers and employees of the University donated blood.

• Competitions : Various competitions like essay, debate, photography, painting etc. were organized for students. A large number of students from university departments and colleges affiliated to Pune University participated in these competitions.

• Sports Rallies : The sports rallies were organized on 2nd October, 1998 at three places, Nashik, Ahmednagar and Pune. These were mainly for general awareness and of various social problems such as AIDS, Drug abuse etc.

• Get-together programmes of past students, past teachers and past nonteaching employees were organized in colleges and university through out the year.

PARTICIPATION IN NATIONAL AND INTERNATIONAL SYMPOSIA, WORKSHOPS REFRESHER COURSES :

Prof. Mali has participated in more than 80 National and International seminars, workshops, symposia and refresher courses. Apart from presenting papers, chaired some sessions in seminars, symposia and conferences. Prof. Mali has been invited for delivering lectures in several workshops and specifically at refresher courses for under graduate and post graduate teachers. Some of the places are mentioned below :

• Indian Institute of Science, Bangalore, June, 1974.

• University of Bern, Switzerland, October, 1979.

• University of Madras, Chennai, January, 1981.

• Banaras Hindu University, Varanasi, October, 1986.

• Shivaji University, Kolhapur, November, 1987.

• Indian Institute of Chemical Technology, Hyderabad, September, 1989.

• UDCT, Mumbai, October, 1990.

• Devi Ahilya Vishwavidyalaya, Indore, September, 1991.

• NOST Conference, Bhuvaneshwar, December, 1992.

• Bhagalpur University, Bhagalpur, November, 1993.

EXTENSION ACTIVITIES :

Prof. Mali is a highly reputed teacher and is quite sought out by for giving lectures at Colleges, Universities and research institutes. He has been invited by more than 75 Research institutes, universities and colleges to deliver lectures on various topics. His aim was to improve the quality of teaching and research at post-graduate centres affiliated to various universities. Prof.Mali has played significant role in the development of research temper at colleges in mofussil areas. Some of the places of his visits are indicated below.

• Swiss Federal Institute of Technology (ETH), Zurich, Switzerland, December, 1979.

• Vikram Sarabhai Space Centre, Tiruvantpuram, December, 1984.

• Mumbai University, Mumbai, October, 1988.

• Dr.B.A.Marathwada University, Aurangabad, February, 1989.

• Kakatiya University, Warangal, December, 1990.

• North Maharashtra University, Jalgaon, Several time since 1990.

• Shivaji University, Kolhapur, January 1993.

• Amravati University, Amravati, February, 1993.

• Sardar Patel University, Vallabhvidyanagar, (Gujarat), January, 1994.

• BARC, Mumbai, September, 1997.

• Karnatak University, Dharwad, October, 1999.

SIGNIFICANT CONTRIBUTION TO RESEARCH :

Professor Mali has been actively engaged in developing newer methods for the synthesis of various carbocyclic and heterocyclic compounds including several natural products. The heterocyclic compounds synthesised include coumarins, isocoumarins, furocoumarins, phthalides, alkylidenephthalides, phthalans, isochromanones, chromenes, coumestanes, phthalimidines, carbazoles, indoles, pyrano- and pyridoindoles, oxazinoindoles, furoquinoline alkaloids, berbine alkaloids and functionalised naphthalenes. Most of these compounds are known to possess useful biological activities and have industrial applications.
Using organolithium and organophosphorus reagents, Professor Mali has developed methods involving fewer steps, to provide the final products in high overall yields. The methods involving lithiation reactions developed for the synthesis of 9,10-oxygenated berbine alkaloids, are unique as they provide substitution pattern which is not easily obtained by the conventional methods. This approach has been extended for the synthesis of 13-alkyl-and 8-alkyl-berbines, providing these compounds in fewer steps and in high overall yields.

The approaches developed by Professor Mali for the synthesis of the relatively inaccessible 6-prenylcoumarins, require only two steps starting from the easily available 2-hydroxy benzaldehydes. In these approaches, five steps viz. Claisen rearrangement, Cope rearrangement, Wittig reaction, isomerisation of the double bond and cyclisation to coumarins occur , in a tandem manner, and provide the final product in high yield. In the synthesis of furocoumarins and pyranocoumarins, four steps, eg. Claisen rearrangement, Wittig reaction, isomerisation of the double bond and cyclisation to form both heterocyclic rings occur in one shot.
Professor Mali has developed three different routes for the synthesis of 8-hydroxyisocoumarins. In one approach the 3-alkyl-7-methoxy phthalides are converted to 3-alkyl-3, 4-dihydro-8-hydroxyisocoumarins in single step just by reacting them with AlCl3 in methylene chloride. In this reaction ring expansion and selective demethylation of 8-methoxy group occur in a single step.
      In the second approach 2-vinyl-6-methoxybenzoic acids are converted exclusively into 3-alkyl-3, 4-dihydro-8-hydroxyisocoumarins simply by reacting them with AlCl3 in methylene chloride. In this approach also the cyclisation and demethylation occur in a single step. The result is in contrast with reported methods for such conversions which give a mixture of 3-alkyl-7-methoxyphthalide and 3-alkyl-3, 4-dihydro-8-methoxyisocoumarins. As the naturally occurring isocoumarins of this type have hydroxyl group at C-8 position, the 8-methoxyisocoumarins are then to be demethylated to 8-hydroxy isocoumarins.

             There are several naturally occurring 3-methyl and 3-alkyl-8-hydroxy-isocoumarins which are reported to possess useful biological activities. Professor Mali has developed a novel, two step method for the 8-hydroxy-3-alkyl isocoumarins from 7-methoxyphthalides. The 7-methoxyphthalides are first converted to 3-(alpha-hydroxyalkyl) 7-methoxyphthalides which are then converted to 8-hydroxy-3-methyl (or -3-alkyl) isocoumarins by reacting them with para-toluene sulphonic acid. In this conversion, ring expansion, dehydration and demethylation occur in a single step. Demethylation with para-toluene sulphonic acid is an interesting observation.

             The methods developed for the synthesis of indole start from 2-nitro-benzaldehydes and require two steps. First step involves Wittig reactions while the second step is generation of nitrene intermediate. This approach has been extended for the synthesis of ethylindole-2-carboxylates, 2-alkyl-indole-3-carboxylates, 2-substituted indoles and oxazinoindoles.

             The 2-substituted indole-3-carboxylates, synthesised above, have been converted to carbazoles and pyrano- and pyrido-indoles. The key step in these transformations involves generation of the anion at alpha -carbon of 2-alkyl group using LDA which is then reacted with aromatic aldehydes or dimethyl acetylene dicarboxylates. In carbazole formation, Michael addition and ring closure occur in a single step.

             Prof. Mali's work has been well appreciated by scientific community. His work has been quoted in several books published by reputed publishers. Some of these are indicated below.

• Reagents for Organic Chemistry by L.F.Fieser and M.Fieser, Volume 9, John Wiley and Sons Inc. U.S.A.

• Advanced Organic Chemistry, Reactions Mechanisms and Structure by Jerry March, Edition 3rd, Wiley Eastern Limited (Indian edition, 1988).

• The Alkaloids, Chemistry and Physiology by R.H.F.Manske and R.G.A.Rodrigo, Volume 17, Academic Press Inc. New York (1979).

• The Alkaloid, Chemistry and Physiology by A.Brossi, Volume 32, Academic Press Inc. New York (1988).

             The Citation Analysis of Prof.Mali's publications indicates that his work is widely quoted in national and international journals. The citation analysis of last ten years (1991-2000) shows that his publications have been cited 194 times.

    ACHIEVEMENTS AS HEAD OF THE DEPARTMENT OF CHEMISTRY :

• Department is recognized by U.G.C. as Centre for Advanced Studies in Chemistry - grant received Rs.80/- Lakhs.

• 300 MHz High Field NMR facility is established.

• Central Computational Facility, with 10 Pentium III computers, is set up only for students.

• A grant of Rs.483/- Lakhs is sanctioned by BARC to establish a National Centre for Free Radical Research.

• DST approved our proposal under IRHPA and sanctioned Rs.20/- Lakhs.

• A proposal under FIST is also approved by DST and sanctioned Rs.65/- Lakhs.

• A matching grant from U.G.C. Rs.7/- Lakhs.

• Earning of Rs.2/- Lakhs (during 2000-2001) for department by providing analytical services and consultancy to private industries and research institutes.

ENCLOSURE - I

RESEARCH PUBLICATION

National :

1. New synthesis of the furoquinoline alkaloids and some oxygen heterocyclic compounds. N.S.Narasimhan and R.S.Mali, Tetrahedron, Lett., 843 (1973).
   

2. Synthesis applications of lithiation reaction - Part VI : New synthesis of linear furoquinoline alkaloids. N.S.Narasimhan and R.S.Mali, Tetrahedron, 30, 4153 (1974)




3. Synthetic applications of lithiation reactions - Part VII : New synthesis of linear and angular naphthofurans and benzocoumarins, N.S.Narasimhan and R.S.Mali, Tetrahedron, 31, 1005 (1975).

4. Synthetic applications of lithiation reactions - Part VIII : A new synthesis of naphtho (1,8-bc)-pyran, N.S.Narasimhan and R.S.Mali, Synthesis, 796 (1975).

5. Synthetic applications of lithiation reactions - Part IX : A simplified synthesis of isocoumarins, N.S.Narasimhan and R.S.Mali, Synthesis, 797 (1975).

6. A novel systhesis of (±) kigelin, B.H.Bhide, V.P.Gupta, N.S.Narasimhan and R.S.Mali, Chemistry and Industry, 519 (1975).

7. Lithiation of methylenedioxybenzene derivatives. A.C.Ranade, R.S.Mali, S.R.Bhide and S.R.Mehta, Synthesis, 123 (1976).

8. A novel synthesis of 2,4-diphenyl-5-methoxypyrimido (5,4-c) quinoline, A.C.Ranade, R.S.Mali, R.M.Gidwani and H.R.Deshpande, Chemistry and Industry, 310 (1977).

9. Convenient synthesis of naturally occurring coumarins, (2-oxo-2H-benzopyrans) and 4-methylcoumarins (4-methyl-2-oxo-2H-benzopyrans), R.S.Mali and V.J.Yadav, Synthesis, 464(1977).

10. Synthesis of halfordamine an alkaloid from Halfordia kendack, R.S.Mali, S.P.Bhagvat and S.S.Kusurkar, Indian J. Chem., 15B, 865 (1977).

11. Novel synthesis of 2,4-diphenylpyrimido (4,5-b) quinoline, A.C.Ranade, R.S.Mali and H.R.Deshpande, Experientia, 40, 584 (1979).

12. Synthetic application of lithiation reactions, Part X : Synthesis of Kokusaginine a furoquinoline alkaloid, N.S.Narasimhan, R.S.Mali and A.M.Gokhale, Indian J. Chem. 18B, 115(1979).

13. Synthetic application of lithiation reactions, Part XIII : Synthesis of 3-phenylcoumarins (3-phenyl-2-oxo-2H-benzopyrans) and 3-phenyl-benzocoumarins (3-phenylnaphthopyrones) N.S.Narsimhan, R.S.Mali and M.V.Barve, Synthesis, 906 (1979).

14. A short synthesis of (R,R) (-) Pyrenophorin from (S) propylene oxide and a 3-pentenoic acid d5 reagent, R.S.Mali, M.Pohmakotr, B.Weidmann and D.Seebach, Liebigs Ann. Chemie., 2272 (1981).

15. d5-Reagents of doubly deprotonated gamma-delta- unsaturated carbonyl derivatives with electrophiles : A novel approach to the synthesis of tetrahydrofurans and tetrahydropyrans, D.Seebach, M.Pohmakotr, C.Sohergenborger, B.Weidmann, R.S.Mali and S.Pohmakotr. Helv. Chim. Acta, 65, 419 (1982).

16. Synthesis of 7,8-dimethoxy and 7,8-methylenedioxy isochroman-3-ones : An efficient synthesis of (±) tetrahydropalmatine and (±) canadiine, N.S.Narasimhan, R.S.Mali and B.K.Kulkarni, Tetrahedron Lett., 22, 2797, (1981).

17. Convenient synthesis of N-methyl 1-(2H)-isoquinolones, R.S.Mali, B.K.Kulkarni and K.Shankaran, Synthesis, 329 (1982).

18. An improved synthesis of maculine, a furoquinoline alkaloid, A.C.Ranade, R.S.Mali and V.M.Kurnaval, Indian J. Chem., 21B, 528 (1982).

19. An improved synthesis of naturally occurring coumarins : Synthesis of herniarin, scoparone and 7-methoxy-6-methylcoumarin, R.S.Mali, V.J.Yadav and R.N.Zaware, Indian J. Chem., 21B, 759 (1982).

20. Synthetic applicaitons of lithiation reactions - Part XVI : Synthesis of (±) tetrahydropalmitine, (±) canadine, (±) stylopine and (±) sinactine, N.S.Narasimhan, R.S.Mali and B.K.Kulkarni, Tetrahedron, 39, 1975 (1983).

21. An improved synthesis of 3-methylcoumarins and their linear and angular benzo derivatives, R.S.Mali, S.N.Yeola and B.K.Kulkarni, Indian J. Chem., 22B, 352 (1983).

22. Synthetic applications of lithiation reactions - Part XVIII : Synthesis of (±) 3,4-dihydro-3-phenylisocoumarins and aglycon of (±) dihydrohomalicine, N.S.Narasimhan, R.S.Mali and B.K.Kulkarni, Indian J. Chem., 22B, 850 (1983).

23. Synthesis of heterocyclic compounds using aromatic lithiation reaction in the key step, N.S.Narasimahn and R.S.Mali, Synthesis, 957 (1983).

24. Synthetic applications of lithiation reactions - Part XIX : A facile synthesis of 7-methoxyphhalide and meconine, N.S.Narasimhan, R.S.Mali, B.K.Kulkarni and P.K.Gupta, Indian J. Chem., 22B, 1257 (1983).

25. Phenolic berbine alkaloids : An improved total synthesis of (±) corypalmine, R.S.Mali and S.N.Yeola, Indian J. Chem., 23B, 79 (1984).

26. Phenolic berbine alkaloids : Total synthesis of (±) discretine, R.S.Mali and S.N.Yeola, Indian J. Chem., 23B, 268 (1984).

27. An unusal reaction of phosphorane with benzoins : Formation of 1,2-dicarbonyl compounds, A.C.Ranade, R.S.Mali and V.M.Kurnaval, Indian J. Chem., 23B, 514 (1984).

28. A convenient total synthesis of (±) cheilanthifoline and (±) tetrahydrogroanlandicine, R.S.Mali and S.N.Yeola, Indian J. Chem., 23B, 818 (1984).

29. A useful synthesis of ethylindole-2-carboxylates and 3,4-dihydrocarbostyrils, R.S.Mali and V.J.Yadav, Synthesis, 862 (1984).

30. A novel synthesis of 1-aryl-7,8-dimethoxy-3-oxo-1,2,3,4-tetrahydroisoquinolines, N.S.Narasimhan, R.S.Mali and B.K.Kulkarni, Synthesis, 114 (1985).

31. A convenient total synthesis of (±) bharatamine and (±) isobharatamine, S.D.Patil and R.S.Mali, Indian J. Chem., 24B, 360 (1985).

32. Useful synthesis of 3-ethyl-and 3,4-dimethylcoumarins : Synthesis of trigoforin, a coumarin from Trigonella foenum-graecum, R.S.Mali, S.G.Tilve, K.S.Patil and Geeta Nagarajan, Indian Journal of Chem., 24B, 1271 (1985).

33. A facile synthesis of 7-methoxyisochroman-3-one : Synthesis of 2,3-dialkoxy-10-methoxyberbines, R.S.Mali, S.L.Patil and Nandini R. Rodricks, Indian J. Chem., 25B, 256 (1986).

34. Novel synthesis of 1-substituted - 7,8-dialkoxyisochroman-3-ones and 8-substitued-2,3,9,10-tetramethoxyberbines, R.S.Mali, S.D.Patil and S.L.Patil, Tetrahedron, 42, 2075 (1986).

35. A novel synthesis of N-substituted-3-carbomethoxymethylphthalimidines, R.S.Mali and S.N.Yeola, Synthesis, 755 (1986).

36. A convenient synthesis of (±) isoochracinic acid, a phthalide from Alternaria kikuchiana, R.S.Mali and S.N.Yeola, Indian J. Chem., 25B, 804 (1986).

37. Heteroatom directed aromatic lithiation reactions for the synthesis of condensed heterocyclic compounds, N.S.Narasimhan and R.S.Mali, Topics in Current Chemistry, 138, 63 (1987).

38. Facile synthesis of ethyl-2-alkylindole-3-carboxylates : Reinvestigation of earlier synthesis of ethyl-3-methylindole-2-carboxylates, M.S.Wadia, R.S.Mali, S.G.Tilve and V.J. Yadav Synthesis, 401(1987).

39. A convenient two-step synthesis of 3-allylcoumarins and their benzoderivatives, R.S.Mali, S.G.Tilve, S.N.Yeola and A.R.Manekar, Heterocycles, 26, 121, (1987).

40. A useful synthesis of alkoxyphthalans (1,3-dihydro-2-benzofurans), R.S.Mali, M.I.Talele and Malayil Koshi, Synthesis, 630 (1987).

41. A novel synthesis of 8-allyl-7-methoxycoumarins, R.S.Mali, A.R.Manekar and S.C.Tilve, Indian J.Chem., 26B, 1007 (1987).

42. An efficient synthesis of coumestan ring system, R.S.Mali and S.G.Tilve, Indian J. Chem., 27B, 4645 (1988).

43. An effcient synthesis of 13-methylberbines, R.S.Mali and S.D.Patil, Indian J. Chem., 27B, 887 (1988).

44. Synthesis of naturally occurring chromenes, R.S.Mali, A.R.Manekar and S.G.Tilve, Indian J.Chem., 27B, 1090 (1988).

45. Synthesis of pentaoxygenated berbines : Total synthesis of (±) O-methylthaicanine, R.S.Mali, A.U.Borse and S.D.Patil, Indian J. Chem., 28B, 107 (1989).

46. A useful synthesis of 2-methyl-2,3-dihydrofuro (2,3-b) quinolines, R.S.Mali and S.G.Tilve, Synth Commun, 19, 1825 (1989).

47. 47. A convenient synthesis of 3-benzyl,-3-benzyl-4-substitued coumarins and their benzodervatives, N.M.Britto, R.S.Mali, V.G.Gore and A.C.Ranade, Synth Commun, 19, 1899 (1989).

48. Total synthesis of (±) thaicanine, R.S.Mali and A.U.Borse, Synthetics Communications, 19, 2613 (1989).

49. A convenient synthesis of 2,3-dihydro-2methyl-5H-furo(2,3-b)(1) bezopyran-5-ones, R.S.Mali, A.R.Manekar and S.G.Tilve, Indian J. Chem., 29B, 113 (1990).

Synthesis of 3-butylidene-7-hydroxyphthalide, R.S.Mali and S.R.Patil, Synth Commun, 20, 167 (1990).

50. A useful synthesis of naturally occurring 3-alkylidenephthalides, R.S.Mali, S.R.Patil, B.K.Kulkarni and S.N.Yeola, Indian J. Chem., 29B, 319 (1990).

51. Useful synthesis of Coumestans, R.S.Mali and S.G.Tilve, Synth Commun, 20, 1781 (1990).

52. Convenient synthesis of 2-vinylindoles, R.S.Mali and S.G.Tilve, Synth Commun, 20, 2041 (1990).

53. Convenient synthesis of naturally occurring methoxy and hydoxyphthalides, R.S.Mali, P.G.Jagtap and S.G.Tilve, Synth Commun, 20, 2841 (1990).

54. 55. Efficent synthesis of (E)-stilbenes, R.S.Mali and P.G.Jagtap, Synth Commun, 21, 841 (1991).

55. Convenient synthesis of Nishoutin (cycloobliquetin), A furocoumarin, isolated from the Heartwood of Pteroxylon obliiquum, R.S.Mali, A.R.Manekar and S.G.Tilve, Org.Prep.Proc.,Int. 24, 52 (1992).

56. Convenient synthesis of dimethyl-1-aryl-4-hydroxy-N-methylcarbazole-2-3-dicarboxylates via Michael initiated Ring Closure methodology, R.S.Mali and P.G.Jagtap, Tetrahedron Lett., 33, 1655 (1992).

57. Novel AICI3 catalysed synthesis of Naturally occurring (±) 8-Hydroxy-3-methyl-3,4-dihydroisocoumarins, R.S.Mali, P.G.Jagtap, S.R.Patil and P.N.Pawar, J.Chem.Soc.Chem.Comm, 883 (1992).

58. Convenient synthesis of 3-aryl-3, 4-dihydroisocoumarins and lunularic acid derivatives, R.S.Mali and D.W.Shelke, Indian J. Chem., 32B, 822 (1993).

59. Stereospecific synthesis of (Z)-3-alkylidenephthalides, R.S.Mali and P.G.Jagtap J. Chem. Resi., (S), 184 (1993).

60. Synthesis of dimethyl-1, 4-dihydroxy-5,6,8-trimethoxy-naphthalene-2,3-dicarboxylate : A key intermediate for fredericamycin-A., R.S.Mali and P.G.Jagtap, Org. Prep. Proc. Int., 25, 633 (1993).

61. Efficient synthesis of 6-phenylcoumarins : Total synthesis of suberosin, toddaculin, O-methylapigravin (O-methylbrosiperin) and O-methylbalsemiferone, R.S.Mali, P.K.Sandhu and A.Manekar-Tilve, J.Chem.Soc. Chem.Commun., 251 (1994).

62. Activated alumina promoted reaction of aldehydes with ethyldiazoacetate : A simple route to B-oxoesters, D.D.Dhavle, P.N.Patil and R.S.Mali, J.Chem.Res., (S), 152 (1994).

63. Pentaoxygenated berbines : Total synthesis of (±) O-methylcapauridine and (±)-O, O, -dimethyl stephabinamine, R.S.Mali, Y.T.Bodkhe and N.V.Gulhati, J.Indian Inst. Science, 74, 205 (1994).

64. Useful synthesis of pyro-and pyridoindoles, R.S.Mali and A.Manekar-Tilve, Org. Prep. Proc., Int., 26, 573 (1994).

65. Useful synthesis of 8-allyl 5,7-dimethoxycoumarins, R.S.Mali and P.K.Sandhu, Synth Commun, 24, 2883 (1994).

66. Useful synthesis of 2-benzylindoles, R.S.Mali, K.N.Babu and P.G.Jagtap J.Chem.Res. (S), 114 (1995).

67. Facile synthesis of 3-Chlorocoumarins, R.S.Mali and J.V.Deshpande, Org. Prep. Proc. Int., 27, 671 (1995).

68. Activated alumina promoted stereoslective Wittig reaction, D.D.Dhavale, M.D.Sindkhedkar and R.S.Mali, J. Chem. Res. (S), 414 (1995).

69. Synthesis of 6-allylcoumarins unoxygenated at C-7 position, R.S.Mali and Archana P. Massey, Indian J. Chem., 34, 6856 (1995).

70. Convenient two-step synthesis of Seselin and Angelicin Derivatives, R.S.Mali, N.A.Pandhare and M.D.Sindkhedkar, Tetrahedron Lett., 36, 7109, (1995).

71. Synthesis of 7-deoxy-8-allylcoumarins R.S.Mali, A.S.Walture and K.N.Babu, Org. Prep. Proc. Int., 28, (1996).

72. Heteroatom directed lithiation reaction in organic synthesis : Synthesis of 3-styrilphthalans and functionalised naphthalenes, R.S.Mali, P.G.Jagtap and A.U.Borse, Indian J. Chem., 35B, 116 (1996).

73. One-Pot Wittig reaction and Clasien rearrangement of 2-hydroxy-4-prenyloxybenzaldehyde and 2-hydroxy-4-prenyloxy-acetophenones : Synthesis of 2', 3', 3'-Trimethyl 2', 3'-dihydroangelicins. R.S.Mali and Paramjeet Kaur Sandhu, J.Chem. Res. (S), 148, 1996.

74. Convenient Synthesis of 1-butyl-2,3,5-trioxygenated benzenes : Synthesis of the di-o-methyl ether of aglycone of cesternoside A, R.S.Mali, M.P.Garkhedkar, M.D.Sindkhedkar and D.D.Dhavale, J.Chem. Res. (S), 342 (1996).

75.  Synthesis of 3,4-dihydro-[1,3]-oxazino [3,4]-indol-1-ones, R.S.Mali and Milind P. Garkhedkar, J.Chem. Res. (S), 496 (1996).

76. Convenient Synthesis of 3-styrylphthalides. R.S.Mali and Archna P. Massey, Synth. Commun., 27, 1049 (1997).

77. A new route to aminosugars from sugar nitrones : Synthesis of 6-deoxynojirimycin D.D.Dhavale, V.N.Desai, M.D.Sindkhedkar, R.S.Mali, C.Castellari and C.Trombini, Tetrahedron Asymmetry, 8, 1475 (1997).

78. An unusual AICI3 catalyzed aromatic cyclization reaction : novel synthesis of tetrahydronaphthoic acids. R.S.Mali, M.D.Sindkhedkar and P.G.Jagtap Tetrahedron Lett. 39, 114 (1998).

79. Reaction of 3-(1-Hydroxyalkyl) phthalides with acids : Synthesis of (Z)-3-Alkylidenephthalides and 3-alkyl-8-hydroxyisocoumarins, R.S.Mali and K.N.Babu, J.Org.Chem. 63, 2488 (1998).

80. Synthesis of naturally occurring (Z)-3-benzylidene and (±) 3-benzylphthalides, R.S.Mali, Archana P.Massey and M.I.Talele, J.Chem. Res. (M), 472 (1998), J.Chem. Res. (S), 68 (1998).

81. Synthesis of naturally occurring 5-allyl-2-aryl-7methoxybenzofuran and 2-aryl-5-(3-hydroxypropyl)-7-methoxybenzofurans, R.S.Mali and A.P.Massey, J.Chem.Res.(M), 1109 (1998), J.Chem. Res.(S), 230 (1998).

82. Naturally occurring prenylated phthalides : First total synthesis of Salfredin B11, R.S.Mali and K.N.Babu, J.Chem.Res.(M), 1215 (1998), J.Chem.Res.(S), 292 (1998).

83. Synthesis of 6-prenylflavanones : Total synthesis of (±) maxima flavanone A, R.S.Mali and Priya Kulkarni-Joshi, Indian J.Chem., 38B, 596 (1999).

84. Synthesis of 2-acyl-and 2-benzoylindoles. R.S.Mali, Santosh G. Tilve and Vidya G. Desai J.Chem. Res., (S), 8, 2000, J.Chem. Res. (M), 150 (2000).

85. Useful synthesis of prenylated - and pyrano-3-arylcoumarins. R.S.Mali and Priya P.Joshi Synth. Commun., 31, 2753 (2001).

86. 3-Aryl-8-hydroxy-3,4-dihydroisocoumarins : Synthesis of aglycones of macrophyllosides A, B and C, R.S.Mali and K.N.Babu, J.Indian Inst. of Science 81, 103 (2001).

87. Synthesis of naturally occurring cinnamyl cinnamates. R.S.Mali and A.S.Papalkar J.Chem.Res. (S), 433 (2001).

88. A short and efficient synthesis of enantiopure (±) N-Boc-7-azabicyclo [2.2.1] heptan-2-one utilising an asymmetric desymmetrization protocol : Formal total synthesis of (-) epibatidine. G.Pandey, S.K.Tiwari, R.S.Singh and R.S.Mali, Tetrahedron Lett, 42, 3947 (2001).

89. Expedient synthesis of naturally occurring (±) 3-benzylphthalides and (±) 3-aryl-8-hydroxy-3,4-dihydro-isocoumarins : Structure revision of (±) 3-benzylphthalide isolated from Frullania falciloba. R.S.Mali, K.N.Babu and P.G.Jagtap, J.Chem.Soc. Perkin Trans 1, 3017 (2001).

90. Efficient synthesis of 6-prenylcoumarins and linear pyranocoumarins : Total synthesis of suberosin, toddaculin , O-methylapigravin (O-methylbrosiperin), O-methylbalsamiferone, dihydroxanthyletin, xanthyletin and luvangetin. R.S.Mali, P.P.Joshi, P.K.Sandhu and A.Manekar-Tilve, J.Chem.Soc.Perkin Trans 1, 371 (2002).

91. Useful synthesis of arylcinnamates : Synthesis of difengpin. J,Chem. Res. (S), 603(2003).

92. Useful Synthesis of arylcinnamates :Synthesis of Difengpin.R.S.Mali and A.S.Papalkar,J.Chem.Res. (S) 603 (2003),J. Chem. Res. (M) 1001 (2003).

93. Intramolecular witting reactions:A new synthesis of commarins and 2-quinolones. V.G.Desai, J.B. Shet, S.G. Tilve and R.S.Mali, J.Chem Res. (S) 628 (2003).

List of M.Phil. and Ph.D. Students guided by Professor R. S. Mali

M.Phil. Students :

All the thirteenM.Phil. students are working as lecturers in undergraduate colleges affiliated to Pune University and North Maharashtra University. They have completed the M.Phil. degree under Faculty Improvement Programme of U.G.C.

ENCLOSURE - III

Ph.D. Students